Antibacterial, Cytotoxic and Antioxidant Activity of Passiflora Edulis Sims

The petroleum ether and chloroform fractions of ethanol extract of leaf and stem from the plant Passiflora edulis (Fam: Passifloraceae) was subjected to antioxidant, antibacterial and cytotoxic activity. All the fractions showed potent antioxidant activity, of which the chloroform and petroleum ether fraction of stem demonstrated the strongest antioxidant activity with the IC50 value of 51.28 μg/ml and 54.01 μg/ml, respectively. In case of antibacterial screening, crude chloroform extract of leaf showed moderate antibacterial activity ranged from 7-10 against twelve microorganisms at a concentration of 500 μg/disc but no activity is observed by the petroleum ether extract. The crude chloroform and petroleum ether extracts of stem showed notable antibacterial activity at a concentration 500 μg/disc ranged from 8-17 and 7-12 respectively against twelve microorganisms However, in the brine shrimp lethality bioassay, all the crude extracts of leaf and stem possessed considerable cytotoxic activity. It was evident that, the chloroform and petroleum ether extracts of stem and leaf have significant cytotoxic potentials with the LC50 value of 6.63 μg/ml, 6.89 μg/ml and 7.91 μg/ml 11.17μg/ml respectively. Antibacterial, Cytotoxic and Antioxidant Activity of Passiflora Edulis Sims 593